Diabetes Medicine And Weight Loss
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How Is The Pancreas Linked With Diabetes
Diabetes is characterized by high blood sugar. This results from insufficient insulin production or function, which can be one effect of problems with the pancreas.
People with diabetes experience high or low blood sugar levels at different times, depending on what they eat, how much they exercise, and whether they take insulin or diabetes medication.
Type 1 and type 2 diabetes both involve the pancreas.
How Can I Manage My Type 2 Diabetes
Managing your blood glucose, blood pressure, and cholesterol, and quitting smoking if you smoke, are important ways to manage your type 2 diabetes. Lifestyle changes that include planning healthy meals, limiting calories if you are overweight, and being physically active are also part of managing your diabetes. So is taking any prescribed medicines. Work with your health care team to create a diabetes care plan that works for you.
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What Happens When Your Body Does Not Produce Enough Insulin
Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Insulin is a hormone that regulates blood sugar. Hyperglycaemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads
How Should Glycemic Targets Be Altered
The simplest and most often discussed modification of usual therapy for people thought to be at high risk is to modify the HbA1c target range. Instead of seeking HbA1c< 53 mmol/mol , higher-risk individuals are commonly advised to aim for between 53 and 64 mmol/mol . Although this was the target range for the standard treatment arm in ACCORD, evidence arguing that this range is always the most appropriate remains limited. For example, individuals with limited life expectancy and having HbA1c of 7586 mmol/mol probably have little to gain from strenuous efforts to reduce this value to < 64 mmol/mol . Similarly, people with serious medical illnesses requiring complex treatments, such as those with cancer undergoing treatment with cytotoxic regimens, might not need to seek even a relaxed HbA1c target range . However, very high HbA1c levels are associated with an acute risk of increased infection and vascular thrombosis as noted above , as well as tiredness, weight loss, and inconvenient polyuria.
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Researchers Explain Why Insulin Production Decreases In Type 2 Diabetes
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Insulin Blood Sugar And Type 2 Diabetes
Insulin is a key player in developing type 2 diabetes. This vital hormoneyou cant survive without itregulates blood sugar in the body, a very complicated process. Here are the high points:
- The food you eat is broken down into blood sugar.
- Blood sugar enters your bloodstream, which signals the pancreas to release insulin.
- Insulin helps blood sugar enter the bodys cells so it can be used for energy.
- Insulin also signals the liver to store blood sugar for later use.
- Blood sugar enters cells, and levels in the bloodstream decrease, signaling insulin to decrease too.
- Lower insulin levels alert the liver to release stored blood sugar so energy is always available, even if you havent eaten for a while.
Thats when everything works smoothly. But this finely tuned system can quickly get out of whack, as follows:
- A lot of blood sugar enters the bloodstream.
- The pancreas pumps out more insulin to get blood sugar into cells.
- Over time, cells stop responding to all that insulintheyve become insulin resistant.
- The pancreas keeps making more insulin to try to make cells respond.
- Eventually, the pancreas cant keep up, and blood sugar keeps rising.
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If Not Controlled At The Right Time Diabetes Can Lead To Kidney Failure Partial Or Complete Blindness Nerve Problems Loss Of Limbs And Increase The Risk Of A Heart Attack
Insulin, which is produced by the pancreas in the body, helps control the bodys blood sugar level. Regular insulin intake along with a proper diet and exercise plan is recommended for type 2 diabetes patients to help maintain their blood sugar level. If not controlled at the right time, diabetes can lead to kidney failure, partial or complete blindness, nerve problems, loss of limbs and even increase the risk of a heart attack. However, there are several myths around injecting insulin due to lack of awareness.
A study, published in the American Medical Associations biomedical journal JAMA Network Open, also found that the relative risk of death due to diabetes itself was much stronger among individuals who were underweight. The findings suggest that there is an urgent need to develop diabetes management programs that are tailored to Asian populations and the subsequent strong implementation of these programs in Asia.
Why do Type 2 diabetics need insulin?
The pancreas, that produces digestive enzymes, is also responsible for producing insulin, a hormone that helps regulate blood sugar levels. Insulin helps the body use the carbohydrates in food for energy. If a patient develops Type 2 diabetes, their pancreas stop producing sufficient insulin that is required for the body to control blood sugar level, said Dr Roopak Wadhwa, consultant, department of diabetes endocrinology and metabolism at Fortis Hospital.
Tips while taking insulin injections
The Pancreas And Type 1 Diabetes
In type 1 diabetes , the beta cells that produce insulin are attacked by the bodys immune system.
As more beta cells get killed off, the pancreas struggles to produce enough insulin to keep blood sugar levels down and the symptoms of diabetes begin to appear.
Research has shown that whilst many beta cells are killed off, the body can continue to produce very small amounts of insulin even after decades have passed.
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Will I Need Medication Or Insulin For Type 2 Diabetes
Some people take medication to manage diabetes, along with diet and exercise. Your healthcare provider may recommend oral diabetes medications. These are pills or liquids that you take by mouth. For example, a medicine called metformin helps control the amount of glucose your liver produces.
You can also take insulin to help your body use sugar more efficiently. Insulin comes in the following forms:
- Injectable insulin is a shot you give yourself. Most people inject insulin into a fleshy part of their body such as their belly. Injectable insulin is available in a vial or an insulin pen.
- Inhaled insulin is inhaled through your mouth. It is only available in a rapid-acting form.
- Insulin pumps deliver insulin continuously, similar to how a healthy pancreas would. Pumps release insulin into your body through a tiny cannula . Pumps connect to a computerized device that lets you control the dose and frequency of insulin.
Diabetes And Endocrine Function
An estimated 30 million Americans have diabetes, a disease in which there is too much sugar in the bloodstream. About 7 million of them, however, have not yet been diagnosed with the disease.
Endocrine Connection
Diabetes occurs when the pancreas, a gland behind the stomach, does not produce enough of the hormone insulin, or the body cannot use insulin properly. Insulin helps carry sugar from the bloodstream into the cells. Once inside the cells, sugar is converted into energy for immediate use or stored for the future. That energy fuels many of our bodily functions.The body produces glucose from the foods you eat. The liver also releases sugar when you are not eating. The pancreas produces the hormone insulin, which allows glucose from the bloodstream to enter the bodys cells where it is used for energy. In type 2 diabetes, too little insulin is produced, or the body cannot use insulin properly, or both. This results in a build-up of glucose in the blood.
People with diabetes are at risk of developing serious health problems . If your blood glucose level stays too high for too long, complications can include:
- Kidney disease and failure
- Nerve damage which can result in nerve pain or injury to the feet or other extremities without feeling pain
There are three blood tests that can be used to check the levels of glucose in your blood and diagnose prediabetes or diabetes:
- Increased thirst
- Constantly feeling tired
- Overweight and obesity
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Who Are The Largest Diabetes Drugs In The World
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Making The Switch To Insulin
Making the transition is much easier than it used to be because most patients are started on a long-acting insulin that does not need to be matched with food intake.
Insulin pens that are preloaded are replacing insulin that needs to be drawn up into a syringe. Patients may still be worried about giving themselves injections, but because the needle is so tiny the adjustment is often quick.
Toujeo and Lantus are long-acting forms of insulin that are available in a prefilled injectable pen.
Thereâs also a type of rapid-acting insulin, Afrezza, that can be inhaled through the mouth via an inhaler.
And a new class of medication called sodium-glucose cotransporter 2 inhibitors is also available now, according to Mazhari. âIt works via a different pathway thatâs not pancreas-dependent, offering another medical therapy option for patients with type 2 diabetes.â
The key to an easy transition to insulin is education.
âPatients need to know how to take their insulin properly since there are many formulations on the market, including short- and long-acting insulin and premixed,â Mazhari said. âMost can be started on a long-acting insulin once a day, though for some patients short-acting or mealtime insulin may be necessary as well. Insulin doses need to be further adjusted depending on blood sugar readings.â
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Guidelines For Starting Insulin
Know your health care providerâs plan up front. Ask what A1C and blood glucose measures are used and how you will start taking insulin.
Think short-term, not long-term. Start taking insulin when your health care provider recommends it, and notice if you feel better and have more energy. Donât try to put it off from appointment to appointment.
Ask to be referred to a diabetes education program to learn the ins and outs of taking insulin and get the support you need.
Have a plan with your health care provider to be in touch regularly to increase your dose until you hit your blood glucose targets.
Get the inside scoop from people who have successfully transitioned to insulin. Try attending a support group or connecting with people willing to support you in one or more of the diabetes online communities.
Explore your options for insulin delivery â using the traditional vial and syringe, or using the more contemporary and convenient pens or possibly an insulin pump. Check your health insurance plan to see what it covers.
Continue to eat well and exercise regularly.
Strive for consistency. Take your insulin and eat at similar times every day when possible.
Store insulin properly. Keep the pen or vial of insulin at room temperature , and store extras in the refrigerator.
Carry a source of carbohydrate to treat low blood sugar, such as glucose tablets or hard candy. Start by using 15 grams of carbohydrate.
What Happens If I Have Too Little Insulin
People with diabetes have problems either making insulin, how that insulin works or both. The main two types of diabetes are type 1 and type 2 diabetes, although there are other more uncommon types.
People with type 1 diabetes produce very little or no insulin at all. This condition is caused when the beta cells that make insulin have been destroyed by antibodies , hence they are unable to produce insulin. With too little insulin, the body can no longer move glucose from the blood into the cells, causing high blood glucose levels. If the glucose level is high enough, excess glucose spills into the urine. This drags extra water into the urine causing more frequent urination and thirst. This leads to dehydration, which can cause confusion. In addition, with too little insulin, the cells cannot take in glucose for energy and other sources of energy are needed to provide this energy. This makes the body tired and can cause weight loss. If this continues, patients can become very ill. This is because the body attempts to make new energy from fat and causes acids to be produced as waste products. Ultimately, this can lead to coma and death if medical attention is not sought. People with type 1 diabetes will need to inject insulin in order to survive.
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How To Get Free Prescriptions For Diabetes Medicine
Youâre entitled to free prescriptions for your diabetes medicine.
To claim your free prescriptions, youâll need to apply for an exemption certificate. This is known as a PF57 form. To do this:
- fill in a form at your GP surgery
- you should get the certificate in the post about a week later itâll last for 5 years
- take it to your pharmacy with your prescriptions
Save your receipts if you have to pay for diabetes medicine before you receive your exemption certificate. You can claim the money back if you include the receipts along with your completed PF57 form.
What Type 2 Diabetic Medications Not Affect The Kidneys
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When Should I See My Doctor
If you have any of the symptoms above, you should make an appointment with your doctor to discuss them since they might indicate undiagnosed type 2 diabetes.
Your doctor will look at your symptoms, review any risk factors you have for type 2 diabetes and they will recommend you be tested if needed.
Even if you dont have symptoms, all Australians should be screened for type 2 diabetes, every 3 years, starting at 40 years of age. Aboriginal and Torres Strait Islander peoples should start screening at age 18. Your GP should carry out this screening. It may involve reviewing your risk factors only, or you may need a blood test.
Video provided by Diabetes Victoria.
Type 2 diabetes can also affect your mental health and can make you more vulnerable to anxiety or depression. SANE Australia and Diabetes Australia have produced a guide to good mental health for people affected by diabetes.