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Pendulum Glucose Control Side Effects

Tips For Success From The Rd

Do Pendulum Probiotics Help Diabetes?

Are you looking for ways to change your lifestyle that will positively impact your type 2 diabetes diagnosis? Here are some of my tips for success.

Weight Control

Weight control is extremely important when you have type 2 diabetes. Dropping a number of pounds to bring you back to a healthy weight level cant cure you of diabetes, but it can help you better manage your glucose levels. You can also reverse many of the side effects that youve experienced from your condition. Consider a healthier diet that is approved for type 2 diabetes, combining it with a regular exercise regimen.

Healthier Diet

A plant-based diet is extremely beneficial for people who have type 2 diabetes. Fruits and veggies dont result in as dramatic of a glucose spike as a lot of other processed foods do. Work more salads, smoothies and vegetable-based soups into your diet.


Add more fiber to your diet to slow down the absorption of sugars into the bloodstream. This keeps your blood sugar levels more controlled.

Managing Type 2 Diabetes

Keeping your blood sugar well controlled is key to reducing your risk of long-term complications such as heart, kidney or eye problems.

Regardless of whether you need medication or which medication you are taking, diet and lifestyle play a key part in preventing long-term complications. You can find out more about how you can improve your diabetes control with diet from our separate leaflet called Type 2 Diabetes Diet.

The initial stages in type 2 diabetes treatment are usually to follow a healthy diet, lose weight if you are overweight, and do regular physical activity. If lifestyle advice does not control your blood glucose levels then medicines are used to help lower these levels. One medicine is used first but two or even three medicines may be needed.

In addition to controlling your blood glucose, keeping raised blood pressure, cholesterol and other risk factors under control are also important. You can read more about controlling other risk factors in our separate leaflet called Type 2 Diabetes.

The rest of this leaflet is about medications to control blood glucose.

New Report Explains Microbiome Impact On Glucose Controlhighlights How Probiotic Interventions Can Improve Type 2 Diabetes Management

A new study by Pendulum Therapeutics was presented at the American Diabetes Associations 81st Scientific Sessions. Its findings show Pendulum Glucose Control increases circulating butyrate and ursodeoxycholic acid , a secondary bile acid in people with type 2 diabetes, and supports the mechanism for improvement in glucose control.

This study, part of an ongoing series, is adding to the body of knowledge on the microbiome and its role in metabolic disease including type 2 diabetes, says Society member Orville Kolterman, MD, chief medical officer at Pendulum Therapeutics and principal investigator of the study. This data builds upon the research Pendulum Therapeutics presented at ADAs 79th Scientific Sessions two years ago. Our initial presentation showcased the efficacy of Pendulums proprietary microbiome symbiotic formulation and its ability to improve glucose control in patients with Type 2 Diabetes. This newest data will further inform the development of a portfolio of products that target the microbiome as a pathway to augment the dietary management of impaired glucose metabolism and other metabolic diseases.

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What Is Pendulum Glucose Control

Pendulum Glucose Control was the first product to be released by Pendulum Therapeutics. There are other medical probiotics that you will find on the health and wellness market, but Glucose Control is one of the best. It includes five powerful probiotic strains along with one prebiotic . This blend is designed to support people suffering from type 2 diabetes. It will manage their A1C and blood sugar levels more effectively to improve quality of life and reduce the risk of side effects.

Behind the Brand

Pendulum Therapeutics is a microbiome-focused company that utilizes DNA sequencing to develop impressive therapies a number of conditions. They are the first of their kind, offering evidence-based glucose control products. Their medical-grade probiotics can be beneficial in the treatment of type 2 diabetes. It is believed that type 2 diabetes may have a connection to an imbalance in the gut microbiome. Creating a more diverse environment could help people better manage their symptoms by aid in fiber digestion and the production of butyrate .

Pendulum Therapeutics Raises $54 Million

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The Series C round nearly doubled the entirety of Pendulums previous raises, bringing the total venture capital raised to $111 million.

As lead investor, Meritech General Partner Craig Sherman will take a seat on the Pendulum Board of Directors alongside Roelof Botha, a partner at Sequoia, and Adam DAugelli, a partner at True Ventures.

We think Pendulum is a next generation pharma company doing next generation gene sequencing, said Sherman. Pendulum could be another 10x Genomics, Datadog, Snowflake or Roblox, which are Meritech investments that went public in the last two years. Pendulum feels like it could be that, because they are creating something that’s truly differentiated and could truly change a person’s life.

Craig, Roelof and I are excited about Pendulum because they are using the microbiome in an entirely new way, to create a never-before-seen product, said DAugelli. Theres a huge white space here. With many supplements, theres no way to tell if theyre even working, while medicines are synthetic and can have side effects. At Pendulum, ingredients are sourced from the microbiome that naturally lives within our bodies, and their formulas are rigorously tested for safety and effectiveness. This new hybrid product Pendulum has created is safe, requires less capital than a drug to bring to market, and could be incredibly beneficial for millions of people.

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Spinal Cord Stimulation Therapy To Treat Chronic Pain Associated With Pdn Approved

In July, Nevro, a spinal cord stimulation company announced receipt of FDA approval of its Senza® System for the treatment of chronic pain associated with Painful Diabetic Neuropathy . This approval is specific to Nevros unique 10 kHz stimulation.

Study participants demonstrated significantly improved and sustained outcomes with 10 kHz Spinal Cord Stimulation , including substantial, sustained pain relief and improved health-related quality of life. The 6-month results for the SENZA-PDN randomized controlled trial were published in JAMA Neurologyin April 2021, and the 12-month follow-up results and 6-month crossover patient data were recently presented at the American Diabetes Association 81st Scientific Sessions in June.

The substantial pain relief and improved quality of life demonstrates that 10 kHz Therapy can safely and effectively treat this patient population, says Erika Petersen, MD, professor of Neurosurgery, director of Functional and Restorative Neurosurgery at the University of Arkansas for Medical Sciences, and lead investigator of the SENZA-PDN study. Im grateful to my co-investigators and the patients who participated in this study, as the results and this approval will have far-reaching impact on the lives of PDN patients.

Who Can Take Glucose Control

If you have been diagnosed with type 2 diabetes and are looking for ways to better manage your condition, you could benefit from the use of Pendulum Glucose Control. This product is intended to be used under the supervision of a medical professional, so youll want to talk to your doctor before starting any kind of product regimen. Not only can you experience better control of your diabetes, but youll reap the benefits of a healthier GI system as well.

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Withings And One Drop Partner To Bring Medical Devices To Multi

Later that month, Withings and One Drop teamed up connect One Drops predictive health platform with Withings smart medical devices for blood pressure and weight management. Together, the companies want to bring connected health solutions to employers, empowering workforces worldwide to make more informed decisions and live healthier lives.

Through this partnership, members enrolled in the One Drop employer program can qualify to receive a Withings Body smart scale or a Withings BPM Connect smart blood pressure monitor in addition to the One Drop glucose meter. Withings devices integrate directly with the award-winning One Drop app, allowing members to seamlessly measure and monitor weight and blood pressure alongside glucose, A1C, food, medications, and physical activity. Members also receive health forecasts powered by nearly 28 billion health data points, one-on-one coaching from certified health professionals, and evidence-based behavioral interventions for chronic disease prevention and management.

Pendulum D2d Glucose Control For Adults With Type 2 Diabetes

Weight-loss side effect prompts shortage of diabetes drug Ozempic
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Recruitment Status : Withdrawn First Posted : January 14, 2020Last Update Posted : October 7, 2021
Condition or disease
Dietary Supplement: Pendulum Glucose Control formulation for T2D Not Applicable

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How Do I Know If My Blood Sugars Are High

Symptoms of high blood sugar in people with diabetes tend to develop slowly over a few days or even weeks. For some people, there may be no physical symptoms until the blood sugar level is very high.

Symptoms of high blood sugar include: increased thirst, needing to pee frequently, recurrent infections such as thrush, bladder infections and skin infection, extreme hunger, tiredness, or unintended weight loss. 3,4

Homeostasis Model Assessment Of Insulin Resistance

Fig 5 shows a forest plot of the pooled effect of probiotics on HOAM-IR. Eight of 17 studies reported changes in HOMA-IR, with 4 studies reporting a significant reduction of HOMA-IR after consuming probiotics. The mean difference ranged from -0.41 to -1.60. The pooled mean difference was -0.48 for HOMA-IR. Significant evidence of inter-study heterogeneity was observed across studies .

Forest plot of randomized controlled trials comparing the effect of probiotics on HOMA-IR with placebo/comparator.

Weighted mean differences for HOMA-IR are shown. Pooled estimates calculated by the random effects method. IV, inverse variance.

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Precautions If You Are Unwell

Some medications commonly prescribed to people with diabetes can cause complications if you are otherwise unwell, particularly if you are dehydrated. These include:

  • SGLT-2 inhibitors.
  • ARBs, which may be used as an alternative to ACE inhibitors.
  • Non-steroidal anti-inflammatory drugs or NSAIDs, used for pain.

If you are taking any of these medicines and become unwell, particularly with diarrhoea and/or vomiting, contact your doctor or nurse. They may recommend that you stop taking some of your medication temporarily. Our leaflet on diabetes and illness gives more advice on what you should do if you are unwell.

How Do I Prevent High Blood Sugars

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In order to keep your blood sugar levels in a healthy range you need to follow your meal plan, exercise program, and medicine schedule. It is important that you:

  • Understand the effect of nutrition, different types of food and how they influence on your personal blood sugar levels
  • Check the influence of type and intensity of exercise on your sugar levels
  • Stay aware of your blood sugar levels by consistently monitoring with Dario, especially in exceptional situations such as sick days, change in dietary habits or physical activity, drug therapy or stress situations 3,4

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Foundations Of Blood Glucose Control

The goal of managing type 2 diabetes is to keep your blood sugar levels in a healthy range. To achieve this, you should make lifestyle changes, including losing weight if you’re overweight, eating a healthy diet and getting regular exercise. If you smoke, you should also get help to quit smoking. You may also need to take medications, such as pills, insulin or other injectable medications. Your health care provider will create a plan tailored to you to help you reach your goals.

Sulfonylurea Medicines As Type 2 Diabetes Treatments

There are several types of sulfonylurea medicines. These include:

They work by increasing the amount of insulin that your pancreas makes.

If you are prescribed a sulfonylurea, usually a low dose is started. The dose can be increased if necessary every few weeks until there is good control of the blood glucose level. You can take a sulfonylurea in addition to other glucose-lowering tablets if one tablet does not control blood glucose well enough on its own.

Possible problems with sulfonylureasSulfonylurea medicines used to be widely prescribed for people whose blood sugar was still too high when they were taking metformin. However, sulfonylureas have several problems not shared by other medications. For this reason, they are no longer recommended as the standard choice after metformin.

Common or important side-effects of sulfonylureas include:

See the leaflet that comes in the medicine packet for full details of cautions and possible side-effects.

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How Do I Treat High Blood Sugar

Treating high blood sugar generally depends on what has caused it. If you have regular occurrences, you should consult with your health care team to review your medicines and/or lifestyle.

You may be advised to:

  • change your diet
  • drink plenty of sugar-free fluids
  • do gentle, regular exercise
  • if you use insulin, you may be advised to adjust your dose

If your blood sugar levels are over 250-300 mg/dL, you should check your urine for ketones. Ketones appear in your urine when your body is breaking down fats for energy, and for people with diabetes, this is an indication that the management of your diabetes needs adjusting. Ketones are more common in someone with type 1 diabetes. They may be present if you have an illness, are dehydrated or have lost weight. Ketones may also appear in someone with type 2 diabetes in the case of illness.

If you have ketones in your urine you should:

  • Correct your dose of insulin and recheck your blood glucose in 1-2 hours.
  • Keep drinking water and rest do not exercise as this can increase the amount of ketones
  • See your health care team to review your treatment plan
  • If you have the following symptoms you should call your doctor as soon as possible:
  • Your blood sugar levels are not going down
  • Your breath smells fruity
  • Acetone in your urine is an extreme condition and you should go directly to the emergency room for treatment.3,4

Monitor Blood Sugar Regularly

Diabetes drug in high demand causing controversy due to weight loss side effect

You can determine daily blood sugar patterns by testing your blood sugar levels regularly throughout the day. This can help you identify the circumstances when your blood sugar levels are at their highest.

Identifying these patterns can help you plan your daily activities and meals to keep your blood sugar levels.

Also Check: What Are The Different Types Of Diabetes

Does The Pendulum Probiotic Work For Type

The wonderful thing about Pendulum Glucose Control is that it uses scientific information to provide the most optimal type 2 diabetes support available. There are a few different aspects to this condition and addressing each of them is what makes this product effective. For example, using these proven strains of probiotics to balance your gut and create a more diverse microbiome can result in better management of your type 2 diabetes symptoms while also reducing your risk of long-term effects.

The Easiest Way To Lower Blood Sugar Naturally With Type 2 Diabetes

If you have type 2 diabetes, chances are you have spent a lot of time learning how to lower your blood sugar levels. And thankfully, there are many natural ways to lower blood sugar with healthy eating and physical activity. For instance, research has found losing 10% of your body weight can lower A1C levels by as much as 0.81%.

Although healthy eating and physical activity can be effective ways to naturally lower blood sugar without medication, they take time and a good deal of effort to pay off . What if there was an easier, scientifically proven way to lower blood sugar naturally that took less than a minute each day? Now there is, and its called Pendulum Glucose Control, the first and only medical probiotic created by Pendulum, a cutting-edge company dedicated to making people healthier through microbiome-targeted solutions.

Pendulum Glucose Control is a safe and natural solution that has been clinically proven to lower A1C levels and blood sugar spikes .* Designed specifically for people with type 2 diabetes, Pendulum Glucose Control contains targeted strains of beneficial bacteria that help restore disrupted gut function, a key component to blood sugar control.

This post has been created in partnership with Pendulum. As always, all opinions are my own

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Pendulum Glucose Control Review: Effective For Type 2 Diabetes

FHM is reader supported – by purchasing through our links, we may earn a small commission.

A big thank you to Pendulum for providing me with the free product, which really helps authenticate my review of Glucose Control – all in an effort to help you decide if it’s right for you!

*Always consult your doctor before using any supplement, including Pendulum Glucose Control*

Fit Healthy Momma Rating: 9/10

Pendulum Glucose Control is a powerful probiotic that’s designed to manage Type 2 diabetes. The Pendulum team created this probiotic with unique strains of good gut bacteria, all in an effort to unlock your metabolic power.

Approximately one in 10 people have diabetes, with 90 to 95 percent of those people suffering from type 2 diabetes. Its most commonly diagnosed in people that are over the age of 45, but its not uncommon for teens and young adults to have it as well.

Many people can look back and see that they were experiencing type 2 diabetes for a number of years before receiving a diagnosis. There are also people who dont experience side effects at all. Its important to watch for type 2 diabetes if you have a family history of the condition. You may also be at risk if youre overweight, live a sedentary lifestyle or experienced gestational diabetes during one or more of your pregnancies.

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