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What Drugs Are Used For Diabetes

Choice Of Insulin Type And Dose


The choice of insulin is complex. Doctors consider the following factors when deciding which insulin is best and how much insulin to use:

  • How well the body responds to the insulin it makes

  • How much the blood glucose level rises after meals

  • Whether other antihyperglycemic drugs can be used instead of insulin

  • How willing and able people are to monitor their blood glucose levels and adjust their insulin dosage

  • How often people are willing to inject insulin

  • How varied daily activity is

Insulin injections can affect the skin and underlying tissues. An allergic reaction, which occurs rarely, causes pain and burning, followed by redness, itchiness, and swelling around the injection site for several hours. Very rarely, a person may have an anaphylactic reaction Anaphylactic Reactions Anaphylactic reactions are sudden, widespread, potentially severe and life-threatening allergic reactions. Anaphylactic reactions often begin with a feeling of uneasiness, followed by tingling… read more after injection of insulin.

What Medicines Could My Doctor Prescribe

Many categories of diabetes medicine are available in pill form: metformin , sulfonylureas, thiazolidinediones, meglitinides, dopamine-2 agonists, alpha-glucosidase inhibitors, sodium-glucose transporter 2 , dipeptidyl peptidase-4 inhibitors, and bile acid sequestrants. Each medicine has good points and bad points. Your doctor will decide which medicine is right for you.

What Are The Types Of Medicines For Type 2 Diabetes

There are several different medicines for type 2 diabetes. Each works in a different way. Many of them are pills. There are also medicines that you inject under your skin, such as insulin.

Over time, you may need more than one diabetes medicine to manage your blood sugar. You might add another diabetes medicine or switch to a combination medicine. A combination medicine contains more than one type of diabetes medicine in the same pill. Some people with type 2 diabetes take both pills and injections.

Even if you don’t usually take insulin, you may need it at special times, such as during pregnancy or if you are in the hospital.

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What Are The Best Drugs To Treat Diabetes

Pharmacy Times

Here are the Top 10 medications in terms of efficacy for lowering A1C and blood sugar levels.

Diabetes is a serious condition that is brought on by decreased insulin secretion from the pancreas and diminished insulin sensitivity in the muscle cells. It is characterized by excessive urination, extreme thirst, high blood sugar, and increased appetite.1

There are a number of medications on the market to help manage this condition, but the following are the top 10 in terms of showing efficacy in lowering A1C and blood sugar levels.

1. Insulin

Patients with type 1 diabetes must be treated with insulin, as the beta cells in their pancreas no longer produce it. Insulin plays a vital role in glucose uptake and is required by the muscle and adipose tissue.2 However, insulin is not solely for patients with T1D those with type 2 diabetes may also be placed on insulin but generally only after failing to reach glycemic targets upon being placed on multiple oral agents for some time. Patients with diabetes typically receive multiple injections per day, including bolus insulin administered before meals and the long-acting basal insulin that lowers blood sugar levels over time. Insulin is classified as a high-risk drug because it can cause patients to experience hypoglycemia, but the benefits of this treatment surely outweigh the risks.2

The most common insulins I see prescribed in my daily practice are Basaglar and NovoLog .

2. Metformin

3. Glipizide

4. Glimepiride

Travelling With Diabetes Medicines

What is the best medication for a Diabetic?

If you’re going on holiday:

  • pack extra medicine â speak to your diabetes nurse about how much to take
  • carry your medicine in your hand luggage just in case checked-in bags go missing or get damaged
  • if you’re flying with a medicine you inject, get a letter from your GP that says you need it to treat diabetes

Page last reviewed: 18 August 2020 Next review due: 18 August 2023

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Taking Empagliflozin With Metformin

There are 4 different strengths of Synjardy. Each tablet contains 5mg or 12.5mg of empagliflozin and 850mg or 1g of metformin. Your doctor will prescribe the right strength of tablet for you.

The usual dose is 1 tablet, taken twice a day. It’s a good idea to take your medicine with a meal. This means the metformin is less likely to upset your stomach.

What Oral Medicines Treat Type 2 Diabetes

You may need to take medicines to manage your type 2 diabetes, in addition to consuming healthy foods and beverages and being physically active. You can take many diabetes medicines by mouth. These medicines are called oral medicines.

Most people with type 2 diabetes start with metformin pills. Metformin also comes as a liquid. Metformin helps your liver make less glucose and helps your body use insulin better. This drug may help you lose a small amount of weight.

Other oral medicines act in different ways to lower blood glucose levels. Combining two or three kinds of diabetes medicines can lower blood glucose levels better than taking just one medicine.

Read about different kinds of diabetes medicines from the FDA.

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What Medicines Might I Take For Diabetes

The medicine you take depends on the type of diabetes you have and how well the medicine controls your blood glucose levels, also called blood sugar levels. Other factors, such as any other health conditions you may have, medication costs, your insurance coverage and copays, access to care, and your lifestyle, may affect what diabetes medicine you take.

What Are The Types Of Medicines For Type 1 Diabetes

Pharmacology – Diabetes Medication

If you have type 1 diabetes, you must take insulin because your body no longer makes it. There are different types of insulin that start to work at different speeds, and the effects of each last a different length of time. Your health care provider will measure your blood glucose to decide on the type of insulin. You may need to use more than one type.

You will also need to check your blood sugar at home. Your provider will tell you how often. The results of your blood sugar testing can help you make decisions about food, physical activity, and medicines.

You can take insulin several different ways. The most common are with a needle and syringe, an insulin pen, or an insulin pump. If you use a needle and syringe or a pen, you have to take insulin several times during the day, including with meals. An insulin pump gives you small, steady doses throughout the day. Less common ways to take insulin include inhalers, injection ports, and jet injectors.

In rare cases, taking insulin alone might not be enough to manage your blood sugar. Then you would need to take another diabetes medicine.

Also Check: Safe Glucose Level For Type 2 Diabetes

How Does Liver Regulate Blood Sugar

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What If I Forget To Take It

Empagliflozin, or empagliflozin with linagliptin

If you miss a dose of empagliflozin or Glyxambi and it’s 12 hours or more until your next dose, take it as soon as you remember. Then take your next dose at the usual time.

If it is less than 12 hours until your next dose, skip the missed dose. Then take your next dose at the usual time.

Empagliflozin with metformin

If you miss a dose of Synjardy, take it as soon as you remember, unless it’s only a few hours until your next dose. In which case miss out the forgotten dose and take your next dose at the usual time.

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Medications For Type 2 Diabetes

If you have type 2 diabetes, your body makes insulin but no longer uses it well.

Your body cant make enough insulin to keep your blood sugar levels normal. The goal of treatment for you is to help your body use your insulin better or to get rid of extra sugar in your blood.

Most medications for type 2 diabetes are oral drugs. However, a few come as injections. Some people with type 2 diabetes may also need to take insulin.

Learn About Lifestyle Changes Medication And Insulin Treatment

Medications for type 2 diabetes (2/5) â VIP Diabetes

Type 2 diabetes is a condition that affects the way your body uses insulin, a hormone that helps regulate your blood sugar. It is often treated with Glucophage , a first-line diabetes drug that reduces the amount of sugar your body produces.

There’s no one-size-fits-all treatment for type 2 diabetes, however. The key to managing this increasingly common condition is piecing together a treatment plan that fits the individual.

Type 2 diabetes treatment may include:

  • Lifestyle changes

This article looks at some of the approved ways to manage and treat type 2 diabetes.

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What Is Type 2 Diabetes

Type 2 diabetes is a chronic disease where the bodys ability to use glucose or sugar as fuel is impaired. Our bodies produce a hormone called insulin which enables sugar from carbohydrates in food we eat to reach the cells and be used as energy. In type 2 diabetes, insulins ability to do its job is compromised, and over time the body actually produces less of it. This means less sugar in the cells for fuel, and more sugar in the blood where it cant be used. Having high levels of blood sugar over time can cause damage to vital organs like the heart, kidneys, nerves, and eyes.

Some risk factors that predispose people to developing type 2 diabetes, such as genetics and age, are not modifiable. Other risk factors, such as being overweight or having obesity, can be altered. This is why losing 5% to 10% of ones baseline weight by healthful eating and physical activity remains the backbone of type 2 diabetes management.

A Combination Of Two Drugs Can Address Three Or Four Defects If We Are Able To Correct Six Defects With Medicines And Lifestyle Changes The Patient Will Be Able To Keep Blood Glucose Levels Under Control It Is Necessary To Use Medicines From Different Classes And Not Just A Higher Dose Of A Single Medicine Says Dr V Mohan President Of The Madras Diabetes Research Foundation

Though we may be keeping our blood sugar levels in check with medication, what really worries us is the constant battle to keep our HbA1c levels below the suggested seven per cent mark. A new study by the US-based National Institute of Health holds out hope. Analysing the effectiveness of four different classes of diabetes medicines in over 5,000 people for years, researchers found that they were almost at par when used with the first-line drug Metformin. But the long-acting insulin glargine and another medicine liraglutide were the best at keeping HbA1c levels within limits. Significantly, despite using the drugs, nearly a fourth of the diabetics werent able to keep their blood glucose levels below the seven per cent mark. Does that mean that using medicines from different classes instead of a higher dose of a single medicine is better for controlling blood glucose levels?

Although the aim of the study was to figure out which drugs work the best for Type-2 diabetes patients, it shows that three-fourths of the diabetics werent able to maintain the target blood glucose levels. Why?

We usually ask patients to control their blood glucose, blood pressure and cholesterol levels. In contrast to diabetes, lipid control is the easiest give the patients statins and the cholesterol levels will come down. Controlling blood pressure is also less complicated, with 48.8 per cent people in our study having it under check.

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How To Lower Your A1c Level Quickly

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How Fast Will Tanzeum Lower My Blood Sugar

Diabetes Drug Could Be Game Changer For Obesity And Weight Loss

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How To Get Free Prescriptions For Diabetes Medicine

If you take diabetes medicine, you’re entitled to free prescriptions for all your medicines.

To claim your free prescriptions, you’ll need to apply for an exemption certificate. This is known as a PF57 form. To do this:

  • fill in a form at your GP surgery
  • you should get the certificate in the post about a week later â it’ll last for 5 years
  • take it to your pharmacy with your prescriptions

Save your receipts if you have to pay for diabetes medicine before you receive your exemption certificate. You can claim the money back if you include the receipts along with your completed PF57 form.

Type 1 Diabetes Medication

The medication insulin is always needed in type 1 diabetes . This is because, with this disease, the immune system destroys insulin-producing beta cells in the pancreas. Without insulin as an escort, glucose in the bloodstream cant get into the cells and remains stuck in the bloodstream. Too much glucose in the bloodstream is called hyperglycemia, a dangerous health condition with many negative consequences. People who have type 1 diabetes must take insulin to survive.

Important information about insulin:

  • It can be taken just once a day or several times per day depending on the individual.
  • Some insulin medication is rapid-acting, working immediately.
  • Other insulin is long-acting, working more slowly but lasting longer.
  • Insulin can be injected with needles via syringe or pen.
  • It can also be delivered with an insulin jet injector that sprays the medication into the body using high-pressure air rather than a needle.
  • Some people use an insulin pump, a small machine connected to a small tube and needle that delivers insulin when needed.

Recommended Reading: How To Check Insulin Resistance

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